Following Bacillus Calmette-Guerin (BCG)-vaccination GMM-reactive T cells produce IFN and TNF in a CD1b-restricted manner (6). containing C80 GMM more potently activated CD1b-restricted T cell line relative to Mo-DCs pulsed with free lipid antigen or antigenic liposomes without Siglec-7 ligand. These data suggest that the endocytic function of Siglec-7 can be exploited to deliver glycolipids … Continue reading Following Bacillus Calmette-Guerin (BCG)-vaccination GMM-reactive T cells produce IFN and TNF in a CD1b-restricted manner (6)